Pancreatic Adenocarcinoma Presenting as First-onset Diabetic Ketoacidosis


The hallmark of diabetic ketoacidosis (DKA) is the triad of hyperglycaemia, ketonaemia and metabolic acidosis. The pathogenesis of DKA involves a relative insulin deficiency and an excess of counterregulatory hormones.1

Interplay between these factors results in reduced glucose utilisation and increased gluconeogenesis, together with increased lipolysis and ketogenesis.


Learning Outcomes

  1. Recognise diabetic ketoacidosis (DKA) has a clinical occurrence in type 2 diabetes.
  2. Learn about a recent study indicating their precipitating factors in people with type 2 diabetes.
  3. Learn why DKA is more common in people from certain ethnic groups with type 2 diabetes.


Medical Journal of Australia
Reading: journal; textbook; book; literature review
0h : 30m
MBA: 0h : 30m
Medical Practitioner, Medical Student, Doctor-in-Training, Non-Vocationally Registered, Nurse / Midwife, Pharmacist, Researcher, Retired, Specialist - Other, Specialist General Practitioner
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