Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand


Paracetamol is a common agent taken in deliberate self‐poisoning and in accidental overdose in adults and children. Paracetamol poisoning is the commonest cause of severe acute liver injury. 

Since the publication of the previous guidelines in 2015, several studies have changed practice. A working group of experts in the area, with representation from all Poisons Information Centres of Australia and New Zealand, were brought together to produce an updated evidence‐based guidance.


Learning Outcomes

  • Explain key components of the revised guideline.
  • List main recommendations.
  • Recognise changes in management as a result of the revised guideline.


Authors: Angela L Chiew, David Reith, Adam Pomerleau, Anselm Wong, Katherine Z Isoardi, Jessamine Soderstrom, Nicholas A Buckley

Article Type: Guideline summary

Medical Journal of Australia
Reading: journal; textbook; book; literature review
1h : 0m
MBA: 1h : 0m
General Medicine
Medical Practitioner, Medical Student, Doctor-in-Training, Non-Vocationally Registered, Pharmacist, Researcher, Retired, Specialist - Other, Specialist General Practitioner
You have to be logged in to see the content of this module.

Provided by

doctorportal Learning respectfully acknowledges Aboriginal and Torres Strait Islander peoples as the first inhabitants of Australia. We respect the traditional owners of lands across Australia in which our members and staff work and live, and pay respect to their elders past, present and emerging.